Senior Director, Health Economics and Outcomes Research (HEOR) / Epidemiology / Real-World Evidence (RWE)

San Francisco, CA
Full Time
Medical Affairs
Aerovate (AVTE) is a clinical stage biopharmaceutical company focused on developing drugs that meaningfully improve the lives of people with rare cardiopulmonary disease. Our team has spent their careers in cardiopulmonary disease research, drug and aerosol development, commercialization and company building.

Our exceptional team of experts, industry veterans, and scientists is uniquely equipped to overcome the current challenges of treating these diseases and deliver novel therapeutics to make a meaningful difference for patients.

At Aerovate, we know the diversity of our team’s backgrounds, talents, skills, and experiences not only makes us unique, but makes us stronger. Tenacious in our pursuit to make a difference and helping each other along the way, we know we can achieve better therapies to make a meaningful impact for patients.

Why Aerovate
Aerovate fosters an uplifting environment, collaborative peers, and a passion for learning that translates into making a difference for people with cardiopulmonary disease and their communities.

Aerovate’s culture is one of inclusion, excellence, and respect in every way – for each other, the science, the community, and our mission. Both at work and in the clinic, we are committed to recruiting individuals that exemplify diversity in culture and life experience and are always striving to grow and improve. We recognize the urgency of our efforts, and we accept the challenge to do what’s right for our patients and their communities.

Position Overview:

We are seeking a highly talented and experienced individual to join our team as the Senior Director of Health Economics and Outcomes Research (HEOR), Epidemiology, and Real-World Evidence (RWE). Reporting directly to the head of medical affairs, the Senior Director will play a pivotal role in leading the development and execution of strategies to generate and leverage real-world evidence to support the launch, development, market access, and commercialization of Aerovate's novel cardiopulmonary therapy.

Duties and Responsibilities:
  • Strategic Leadership: Provide strategic leadership and direction for the HEOR, Epidemiology, and RWE functions, aligning activities with the company's overall objectives and therapeutic focus on rare cardiopulmonary diseases.
  • Evidence Generation Planning: Lead the development of evidence generation plans to support product value proposition, market access, and reimbursement efforts, incorporating HEOR, epidemiological, and RWE methodologies.
  • Study Design and Execution: Oversee the design, implementation, and analysis of HEOR, epidemiological, and RWE studies, including observational research, database analyses, and patient-reported outcomes studies.
  • Data Analysis and Interpretation: Analyze and interpret real-world data to generate insights into disease burden, treatment patterns, comparative effectiveness, and healthcare utilization, informing decision-making and strategy development.
  • Market Access Support: Collaborate with Market Access, Pricing, and Reimbursement teams to develop value dossiers, health economic models, and other tools to support product reimbursement and market access negotiations.
  • Regulatory Compliance: Ensure compliance with all relevant regulations, guidelines, and industry standards governing HEOR, epidemiology, and RWE research, including FDA and EMA requirements.
  • External Collaboration: Build and maintain relationships with key opinion leaders, academic institutions, research partners, and patient advocacy groups to enhance Aerovate's capabilities and reputation in HEOR, epidemiology, and RWE.
  • Team Leadership: Provide leadership, mentorship, and guidance to the HEOR, Epidemiology, and RWE teams, fostering a culture of excellence, collaboration, and innovation.
  • Advanced degree (PhD, MD, PharmD, or equivalent) in health economics, epidemiology, outcomes research, or related field required.
  • Demonstrated years of experience in HEOR, epidemiology, RWE, or related roles within the pharmaceutical or biotechnology industry, with a focus on cardiopulmonary diseases preferred.
  • Expertise in study design, data analysis, and interpretation of real-world data, with a strong understanding of statistical methods and health economic modeling techniques.
  • Demonstrated track record of success in leading cross-functional teams and managing complex projects in a matrixed environment.
  • Excellent communication and presentation skills, with the ability to effectively communicate complex scientific concepts to diverse audiences.
  • Strong leadership skills with the ability to inspire and motivate teams to achieve goals and objectives.
  • Proven ability to think strategically and drive innovative solutions to address business challenges.
  • Experience working in a clinical-stage biopharmaceutical company and collaborating with stakeholders across different geographies and cultures.
  • Competitive salary and performance-based incentives.
  • Comprehensive benefits package, including health insurance, retirement plans, and wellness programs.
  • Opportunities for professional growth and career development.
  • Collaborative and innovative work environment with a focus on making a meaningful impact in patients' lives.
  • Compensation packages will be based on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills.
Aerovate Therapeutics, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination, harassment, or retaliation of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by Federal, State, and Local laws.

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